Dr Sebastian Zeki

Dr Sebastian Zeki is a Consultant Gastroenterologist at Guy’s and St Thomas’ NHS Foundation Trust, one of the UK’s leading tertiary referral centres. He specialises in diseases of the oesophagus and upper gastrointestinal tract, with particular expertise in reflux disorders, Barrett’s oesophagus and complex endoscopic therapy. Dr Zeki completed his medical training in London and undertook specialist gastroenterology training in London, Cambridge and Tokyo. He has developed advanced skills in diagnostic and therapeutic endoscopy, including the management of early neoplastic lesions using advanced endoscopic resection techniques. Alongside his clinical work, Dr Zeki is actively involved in research and service development. His work focuses on improving the understanding and management of oesophageal conditions, including reflux disease and premalignant disorders. He has published in peer-reviewed journals and is committed to delivering evidence-based, patient-centred care. Dr Zeki has a strong interest in the use of data and digital innovation in gastroenterology, particularly in improving endoscopy reporting and clinical outcomes. He is also involved in teaching and training, contributing to the development of future gastroenterologists. In private practice, Dr Zeki offers comprehensive assessment and management of gastrointestinal symptoms, with a particular focus on providing clear diagnoses and tailored treatment plans. He is known for his thorough and thoughtful approach, ensuring patients feel informed and supported throughout their care.

Gastro-oesophageal reflux disease (GORD), including complex and refractory reflux Barrett’s oesophagus, including surveillance and endoscopic therapy Dysphagia and oesophageal motility disorders Eosinophilic oesophagitis (EoE) Upper gastrointestinal endoscopy (gastroscopy) Colonoscopy and lower gastrointestinal endoscopy Advanced endoscopic procedures, including endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) Endoscopic management of early oesophageal and gastric neoplasia Ambulatory reflux monitoring, including BRAVO pH testing Functional gastrointestinal disorders affecting the upper GI tract